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近十年葛根防治骨质疏松症的研究进展
引用本文:孔蓓蓓,刘连起,王新祥. 近十年葛根防治骨质疏松症的研究进展[J]. 环球中医药, 2012, 5(3): 226-230
作者姓名:孔蓓蓓  刘连起  王新祥
作者单位:1. 北京中医药大学基础医学院,100029
2. 北京中医药大学东方医院实验中心
基金项目:基金项目:国家自然科学基金(3087290);国家中医药管理局中医药科学技术研究专项(0607JP02);北京中医药大学创新团队项目(2011-CXTD-23)
摘    要:葛根是一种药食同源植物,含有大量异黄酮。实验研究表明葛根及相关提取物在体内外实验中有增加骨量、改善骨代谢的功能。临床研究发现葛根能改善骨质疏松症病人的骨代谢生化指标,并改善患者的临床症状,一些防治骨质疏松症的中药复方也开始加入葛根,说明葛根治疗骨质疏松症已得到认可并应用于临床。本文对近十年来葛根防治骨质疏松症的研究进展作一综述,并对未来做出展望。

关 键 词:葛根  骨质疏松  骨代谢  异黄酮

Research progress of Radix Puerariae in the prevention and treatment of osteoporosis in recent ten years
KONG Bei-bei , LIU Lian-qi , WANG Xin-xiang. Research progress of Radix Puerariae in the prevention and treatment of osteoporosis in recent ten years[J]. Global Chinese Medicine, 2012, 5(3): 226-230
Authors:KONG Bei-bei    LIU Lian-qi    WANG Xin-xiang
Affiliation:.(School of Basic Medical Sciences,Beijing University of Chinese Medicine,Beijing 100029,China )
Abstract:Puerariae Radix(PR) is an important crude edible herb and one of the earliest traditional Chinese medicine for various medical purposes.The isoflavone is an important ingredient contained in RP with estrogenic-like activity.Laboratory studies indicated that PR can increase bone mass,improve bone metabolism.PR also could improve the life quality of osteoporosis patients in clinical studies.We summarize the effect of PR on osteoporosis in basic and clinical research in the recent ten years,and give prospect to further research.
Keywords:Puerariae Radix  Osteoporosis  Bone metabolism  Isoflavone
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