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Effect of ionizing radiation on the uric acid and allantoin contents of the blood and urine of animals
Authors:T A Fedorova  V P Fedotov  N A Mkrtumova
Abstract:Summary The uric acid and allantoin contents of the blood and urine of dogs and rats receiving lethal doses of gamma-and agr-radiation have been determined. The uric acid contents of the blood and urine fell by 15–45% during the course of radiation sickness, while the allantoin contents rose by 30–50%. The food rations of the control animals were restricted to those of the irradiated ones, and were quantitatively inadequate; the uric acid content of the blood and urine rose under these conditions by 17–20%, and the allantoin content by 12–15%.Experiments on rats with a circulatory by-pass of the liver showed that at the height of radiation sickness the liver removed more uric acid from the blood than normally, but put out more allantoin.Presented by Active Member AMN SSSR A. E. Braunshtein
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