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Leiomyosarcoma of the Right Atrium Masked by a Covering Thrombus: Conflicting Results of Echocardiography and Transvenous Biopsy—In Favor of Echocardiography
Authors:ILAN AUERBACH  M.D.    ALEXANDER TENENBAUM  M.D.  PH.D.    ENRIQUE Z. FISMAN  M.D.    JOSEPH SHEMESH  M.D.    MEORA FEINMESER  M.D.    YITZHAK HERZ  M.D.    ANA TRUJILLO  M.D.    MICHAEL MOTRO  M.D.
Affiliation:Departments of Internal Medicine "B," Pathology and Cardiology, Beilinson Medical Center, Petah-Tiqva, the Cardiac Rehabilitation Institute, Chaim Sheba Medical Center, Tel-Hashomer, and the Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel
Abstract:A 62-year-old woman was admitted for the evaluation of pedal edema and ascitis. Echocardiography revealed a right atrial (RA) mass invading the interatrial septum and extending into the inferior vena cava (IVC). Contrast enhanced computerized tomography scan excluded extravascular involvement. An organized thrombus was diagnosed by transvenous endomyocardial biopsy. The patient was treated with continuous intravenous heparin, and died soon after from hepatic failure. Postmortem histologic examination revealed a leiomyosarcoma surrounded by a thrombus involving RA, IVC, and hepatic veins. Endomyocardial biopsy played a misleading role that affected patient's management.
Keywords:leiomyosarcoma    right atrium    inferior vena cava    thrombus    endomyocardial biopsy    echocardiograph
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