| 肺癌患者血浆肿瘤坏死因子,白细胞介素—2水平测定及其临床意义 |
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| 引用本文： | 李桂香.肺癌患者血浆肿瘤坏死因子,白细胞介素—2水平测定及其临床意义[J].标记免疫分析与临床,1999,6(2):72-74. |
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| 作者姓名： | 李桂香 |
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| 作者单位： | 兰州医学院第二附属医院 |
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| 摘 要： | 本文对４３例肺癌患者检测了血浆中白细胞介素－２（ＩＬ－２）和肿瘤坏死因子（ＴＮＦ）的水平，发现肺癌组的ＴＮＦ较对照组明显升高（Ｐ〈０．０１），但ＩＬ－２较对照组明显降低（Ｐ〈０．０１）。研究结果表明：ＴＮＦ与肺癌的预后和复发有关，ＩＬ－２水平降低提示肺癌患者细胞因子免疫调节网络可能存在缺陷或紊乱，而这各缺陷或紊乱可能与肺癌发生与发展有关。
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| 关 键 词： | 肺癌 白细胞介素－2 肿瘤坏死因子 病理学 |
Clinical Application of Determination of Tumor Necrosis Factor and Interleukin-2 in Lung Cancer Patients |
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| Li Guixiang.Clinical Application of Determination of Tumor Necrosis Factor and Interleukin-2 in Lung Cancer Patients[J].Labeled Immunoassays and Clinical Medicine,1999,6(2):72-74. |
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| Authors: | Li Guixiang |
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| Abstract: | The levels of tumor nercrosis factor(TNF) and interleukin-2(IL-2) were measured in 43 patients with lung cancer and 30 normal subjects. The results indicated that TNF in patients with lung cancer was significantly higher than that of normals (P<0.01),but IL-2 was significantly lower than that of normals (P<0.01).The findings suggested that TNF is one of the causes in judging prognosis sumption and recurrence of lung cancer.The IL-2 level in patients with lung cancer was decreased markedly.This results showed that there may be some defects or disorder of cytokine immune regulation in patients with tumor.These defects or disorder may play an important role in the occurrence and development of lung cancer. |
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| Keywords: | Tumor necrosis factorInterleukin-2Lung cancer |
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