Rifabutin-associated uveitis in an immunosuppressed pediatric patient without acquired immunodeficiency syndrome

Purpose: To describe a case of bilateral, symptomatic rifabutin-associated uveitis with hypopyon and vitreal opacities in an immunosuppressed pediatric patient without acquired immunodeficiency syndrome (AIDS).Method: Case report. An 8-year-old boy presented with bilateral uveitis 24 months after a bilateral lung transplant.Results: Our patient, whose medications included rifabutin, clarithromycin, and immunosuppressive agents, responded to discontinuation of the rifabutin and initiation of intensive topical corticosteroid therapy with complete resolution of the uveitis.Conclusion: Rifabutin-associated uveitis may occur in a non-AIDS pediatric patient.