| 麻黄汤不同配伍对大鼠脑内Glu/GABA比值的影响 |
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| 引用本文： | 魏凤环,罗佳波. 麻黄汤不同配伍对大鼠脑内Glu/GABA比值的影响[J]. 山东中医药大学学报, 2008, 32(3): 228-229 |
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| 作者姓名： | 魏凤环 罗佳波 |
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| 作者单位： | 南方医科大学中医药学院,广东,广州,510515;南方医科大学中医药学院,广东,广州,510515 |
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| 摘 要： | 目的:研究麻黄汤不同配伍对大鼠额叶皮层中谷氨酸/γ-氨基丁酸(Glu/GABA)比值的影响。方法:采用HPLC法测定氨基酸类神经递质的量。结果:桂枝、杏仁、甘草均显著降低了大鼠额叶皮层中Glu/GABA比值(P=0.021,0.007,0.028),且桂枝与甘草(P=0.014)、杏仁与甘草(P=0.009)呈显著的一级交互作用。结论:麻黄汤不同配伍对大鼠额叶皮层中Glu/GABA比值的影响呈规律性变化。
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| 关 键 词： | 麻黄汤 配伍 谷氨酸/γ-氨基丁酸 脑 大鼠 |
| 文章编号： | 1007-659X(2008)03-0228-02 |
| 修稿时间： | 2008-01-11 |
Effects of different compatibility of MahuangTang on the ratio of Glu and GABA in rats |
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| WEI Feng-huan,LUO Jia-bo. Effects of different compatibility of MahuangTang on the ratio of Glu and GABA in rats[J]. Journal of Shandong University of Traditional Chinese Medicine, 2008, 32(3): 228-229 |
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| Authors: | WEI Feng-huan LUO Jia-bo |
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| Abstract: | Objective:To study effects of the different compatibility of MahuangTang(MHT) on the ratio of Glu and GABA in the prefrontal cortex of the rats. Methods:Use HPLC/UV to determine the content of amino acids.Results:Ramulus Cinnamomi,Semen Armeniacae Amarum and Radix Glycyrrhizae had significantly reduced the relative value of Glu and GABA(P=0.021,0.007,0.028).The two-way interaction of Radix Glycyrrhizae and another factors had significant effect on the ratio of Glu/GABA(P=0.014,0.009).Conclusion:The different compatibilities of MHT had regular influence on the ratio of Glu/GABA. |
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| Keywords: | MahuangTang compatibility Glu/GABA brain rat |
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