| 酒饼簕枝叶中的化学成分及其抗菌活性 |
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| 引用本文： | 杨吟宇,左文健,曾艳波,梅文莉,戴好富.酒饼簕枝叶中的化学成分及其抗菌活性[J].中国药物化学杂志,2013,23(4):305-308. |
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| 作者姓名： | 杨吟宇 左文健 曾艳波 梅文莉 戴好富 |
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| 作者单位： | （1. 海南大学 农学院，海南 海口 570228; 2.中国热带农业科学院 热带生物技术研究所 热带作物生物学与遗传资源利用农业部重点实验室, 海南 海口 571101; 3.海南省黎药资源天然产物研究与利用重点实验室, 海南 海口 571101） ; |
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| 基金项目： | 中央级公益性科研院所基本科研业务费专项（1630052012014） |
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| 摘 要： | 目的研究酒饼簕Atalantia buxifolia(Poir.)Oliv.]枝叶的化学成分。方法采用硅胶柱色谱、凝胶柱色谱进行分离。结果与结论根据理化性质和波谱数据鉴定化合物的结构,从中分离得到8个化合物,分别鉴定为glycofolinine(1)、glycosparvarine(2)、5-hydroxyarborinine(3)、1,5,6-trihydroxy-3-methoxy-10-methyl-9(10H)-acridone(4)、东风桔碱(5)、atalantoflavone(6)、对羟基苯乙醇(7)和胡萝卜苷(8)。其中化合物1～4为首次从该植物中分离得到。抗菌活性测试结果表明,化合物3对金黄色葡萄球菌具有抑制活性。
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| 关 键 词： | 酒饼簕 化学成分 吖啶酮生物碱 抗菌活性 |
| 收稿时间： | 2012-11-12 |
| 修稿时间： | 2013-6-20 |
Components from the branches of Atalantia buxifolia (Poir.) Oliv. and their antibacterial activity |
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| YANG Yin-yu,ZUO Wen-jian ZENG Yan-bo MEI Wen-li,DAI Hao-fu.Components from the branches of Atalantia buxifolia (Poir.) Oliv. and their antibacterial activity[J].Chinese Journal of Medicinal Chemistry,2013,23(4):305-308. |
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| Authors: | YANG Yin-yu ZUO Wen-jian ZENG Yan-bo MEI Wen-li DAI Hao-fu |
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| Institution: | (1. College of Agriculture, Hainan University, Haikou 570228, China; 2. Hainan Key Laboratory for Research and Development of Natural Products From Li Folk Medicine, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricaltural Sciences, Haikou 571101, China; 3. Haikou Key Laboratory for Research and Development of Tropical Natural Products, Haikou 571101, China) |
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| Abstract: | The branches of Atlantia buxifolia have been used as a folk medicine to treat flu, cough, malaria and stomachache, etc. Eight compounds were isolated from the branches of A. buxifolia by silica gel, sephadex LH-20 column chromatography, and their structures were identified as glycofolinine (1), glycosparvarine (2), 5-hydroxyarborinine (3), 1, 5, 6-trihydroxy-3-methoxy-10-methyl-9(10H)-acridone (4), atalafoline (5), atalantoflavone (6), p-hydroxy phenylethanol (7) and daucosterol (8) by the spectroscopic analysis. Compounds 1-4 were isolated from A. buxifolia for the first time. Compound 3 showed antibacterial activity against Staphylococcus aureus. |
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| Keywords: | Atalantia buxifolia (Poir ) Oliv chemical constituents acridone alkaloids antibacterial activity |
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