| Institution: | (1) Department of Gastroenterology, Seth Sukhlal Karnani Memorial Hospital & Institute of Postgraduate Medical Education and Research, 244, AJC Bose Road, 700020 Kolkata, India;(2) Department of Pathology, Seth Sukhlal Karnani Memorial Hospital & Institute of Postgraduate Medical Education and Research, 244, AJC Bose Road, 700020 Kolkata, India;(3) Department of Cellular Immunology, Indian Institute of Chemical Biology, Kolkata, India;(4) Science and Instrument center, Burdwan University, Burdwan, India;(5) Department of Microbiology, NRS Medical College, Kolkata, India |
| Abstract: | BackgroundHelicobacter pylori (H. pylori) has been etiologically linked with primary gastric lymphoma (PGL) and gastric carcinoma (GC). There are a few reports of occurrence of both diseases in the same patient with H. pylori infection.Case presentationWe report a patient with PGL in whom the tumor regressed after surgical resection combined with eradication of H. pylori infection. However, he developed GC on follow up; this was temporally associated with recrudescence / re-infection of H. pylori. This is perhaps first report of such occurrence.ConclusionsPossible cause and effect relationship between H. pylori infection and both PGL and GC is discussed. This case also documents a unique problem in management of PGL in tropical countries where re-infection with H. pylori is supposed to be high. |
