Decreased inducibility of TNF expression in lipid-loaded macrophages期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

Decreased inducibility of TNF expression in lipid-loaded macrophages

Authors:	Mikko?PS?Ares author-information" > author-information__contact u-icon-before" > mailto:mikko.ares@medforsk.mas.lu.se" title=" mikko.ares@medforsk.mas.lu.se" itemprop=" email" data-track=" click" data-track-action=" Email author" data-track-label=" " >Email author,Maria?Stollenwerk,Anneli?Olsson,Bengt?Kallin,Stefan?Jovinge,Jan?Nilsson

Affiliation:	1.Lund University, Wallenberg-laboratory,University Hospital MAS,Malm?,Sweden;2.Center for Molecular Medicine, Karolinska Hospital,Karolinska Institutet,Stockholm,Sweden;3.Nya Apodemus AB, Stockholm University, WGI,Arrenius Laboratory F3,Stockholm,Sweden

Abstract:	Background Inflammation and immune responses are considered to be very important in the pathogenesis of atherosclerosis. Lipid accumulation in macrophages of the arterial intima is a characteristic feature of atherosclerosis which can influence the inflammatory potential of macrophages. We studied the effects of lipid loading on the regulation of TNF expression in human monocyte-derived macrophages.

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