| 新生儿脐血和足跟血TSH水平的比较 |
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| 引用本文： | 吴艺捷,时锺孚,张家秀,王鸿涓,刘素华,吴慎兴,杨一平. 新生儿脐血和足跟血TSH水平的比较[J]. 中华内分泌代谢杂志, 1992, 0(3) |
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| 作者姓名： | 吴艺捷 时锺孚 张家秀 王鸿涓 刘素华 吴慎兴 杨一平 |
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| 作者单位： | 贵阳医学院附属医院内分泌科，贵阳医学院附属医院内分泌科，贵阳医学院附属医院内分泌科，贵阳市妇幼保健院新生儿科，贵阳市第一人民医院妇产科，贵阳市第二人民医院妇产科，贵阳市第四人民医院妇产科 550001，550001，550001 |
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| 摘 要： | 为了评价脐血和足跟血用于甲状腺功能减退(甲减)筛查的效果,对同一新生儿配对收集其脐血和足跟血,比较TSH水平。用高灵敏度的免疫放射分析法(IRMA)检测1998例新生儿血斑样品的TSH。出生后1～3天的足跟血均值高于脐血均值,而4～8天时则相反。从频数分布可见生后2天内的足跟血中TSH增高者较脐血多,而3～4天时二者较接近。提示甲减筛查时脐血和足跟血均可使用,而脐血可能较生后2天内的足跟血更好。
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| 关 键 词： | 脐血 足跟血 TSH 甲减筛查 |
COMPARISON OF CORD AND HEEL BLOOD THYROIDSTIMULATING HORMONE LEVELS IN NEONATES |
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| Wu Yi-jie,et al.. COMPARISON OF CORD AND HEEL BLOOD THYROIDSTIMULATING HORMONE LEVELS IN NEONATES[J]. Chinese Journal of Endocrinology and Metabolism, 1992, 0(3) |
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| Authors: | Wu Yi-jie et al. |
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| Affiliation: | Wu Yi-jie,et al.Dept. of Endocrinology,Affiliated Hospital of Guiyang Medical College,Guiyang 550001 |
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| Abstract: | To evaluate the sampling methods for screening neonatal hypothyroidism, we compared cord and heel blood specimens of the same baby. A total of 1 998 pairs of neonatal blood spots TSH values were determined by a highly senstive immunoradiometric assay (IRMA). The results showed that from 1 to 3 days of age, mean TSH values in heel blood were higher than those in cord blood and from 4 to 8 days of age, the values in the former were lower than in the latter. The distribution showed a higher proportion of heel blood samples with raised TSH levels as compared with cord blood when the specimens were collected within 2 days after birth. The distributions were very similar between cord and heel blood samples collected from babies of 3 and 4 days old. Our results indicated that cord blood as well as heel blood can be used for neonatal screening and the former may be better than heel blood collected within 2 days after birth. |
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| Keywords: | Cord blood Heel blood Thyroid-stimulating hormone Neonatal screening |
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