Surrogate markers for atherosclerosis in overweight subjects with atherogenic dyslipidemia: the GEMS project |
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| Authors: | Genoud Myriam Wietlisbach Vincent Feihl François Mermod Alice Morin Diane Darioli Roger Nicod Pascal Mooser Vincent Waeber Bernard Hayoz Daniel Waeber Gérard |
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| Affiliation: | Department of Internal Medicine, CHUV-University Hospital, Lausanne, Switzerland. |
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| Abstract: | Metabolic syndrome is a constellation of major risk factors for cardiovascular disease. In affected individuals with this syndrome, the independent contribution of low high-density lipoprotein-cholesterol and increased triglyceride levels to the development of atherosclerosis remains to be clarified. We assessed the relationship between these 2 parameters and several surrogate markers for atherosclerosis. One hundred and twenty overweight cases, defined as having high-density lipoprotein-cholesterol (or=75 percentile) were compared with 120 discordant overweight controls defined on lipid values (high-density lipoprotein-cholesterol >or=50 percentile and triglycerides
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