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氧氟沙星随机对照治疗细菌性感染的临床评价
引用本文:李家泰 王广厚. 氧氟沙星随机对照治疗细菌性感染的临床评价[J]. 北京医学, 1994, 16(4): 246-251
作者姓名:李家泰 王广厚
作者单位:北京医科大学临床药理研究所,北京市昌平县医院内科,北京市地坛医院,重庆医科大学第一附属医院传染科
摘    要:用国前氧氟沙星与头孢拉定、诺氟沙星进行随机对照临床试验。氧氟沙星头孢拉定对照治疗呼吸道及其它感染各44例,有效率分别为91%和80%,细菌消除率分别88%和82%。氧氟沙星与诺氟沙星治疗泌尿系及肠道感染各57例,有效率分别为95%和84%,细菌消除率分别为96%和87%。两组试验结果统计学处理均无显著性差异。

关 键 词:氧氟沙星 诺氟沙星 头孢拉定

A clinical assessment for randomized controlled treatment with ofloxacin in bacterial infection
Li Jiatai,et al. A clinical assessment for randomized controlled treatment with ofloxacin in bacterial infection[J]. Beijing Medical Journal, 1994, 16(4): 246-251
Authors:Li Jiatai  et al
Abstract:A randomized controlled clinical trial on domestic Ofloxacin , compared with both Cephradine and Norfloxacin,was condueted.In the treatment of respiratory tract , skin and soft tissue infections,the effective rate of Ofloxacin (44 patients) and Cephradine ( 44 patients) were 91%and 80% respectively, the baterial clearance rate of the two groups was 88% and 82% re spectively.114 patients with urinary tract and enteric tract infections were randomized to receive either Ofloxacin (57 patients) or Norfloxacin(57 patients).The effective rate of the two groups were 95% and 84% respectively. the bacterial clearance rate of the two groups was 96% and 87%respectively,There was no statistical difference between Ofloxacin and controls.
Keywords:Ofloxacin Cephradine  Norfloxacin  Randomized control  Clinical trial
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