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复方氧氟沙星涂膜剂的制备与临床疗效观察
引用本文:孙继平,陶金凤.复方氧氟沙星涂膜剂的制备与临床疗效观察[J].药学实践杂志,2006,24(5):283-285.
作者姓名:孙继平  陶金凤
作者单位:南京医科大学第三附属医院,江苏,仪征,211900
摘    要:目的:制备复方氧氟沙星涂膜剂并进行疗效观察。方法:采用壳聚糖为基质,制备含氧氟沙星、盐酸丁卡因等药物的涂膜剂,建立制剂质量控制方法,并进行临床疗效观察。结果:该制剂制备工艺简单,质量可靠,治疗复发性口疮有效率达98.8%。结论:该制剂制备工艺简单,疗效确切,临床使用安全可靠。

关 键 词:氧氟沙星  盐酸丁卡因  壳聚糖  涂膜剂  疗效观察
文章编号:1006-0111(2006)05-0347-03
收稿时间:2005-11-16
修稿时间:2005年11月16

Preparation and observation of clinical effect of compound ofloxacin film
SUN Ji-pin and TAO Jin-feng.Preparation and observation of clinical effect of compound ofloxacin film[J].The Journal of Pharmaceutical Practice,2006,24(5):283-285.
Authors:SUN Ji-pin and TAO Jin-feng
Institution:The Third Affiliated Hospitial of Nanjing Medical University, Yizheng 211900, China
Abstract:Objective:To prepare compound ofloxacin film and observe its clinical effect.Methods:Chitosan was used as the base material to make compound film which including drugs such as ofloxacin,tetracaine hydrochloride and so on.The quality control meth- od of the film was established and the clinical effect was observed.Results:The prepare technique is simple and the quality control is reliable.The effective rates of using the film to treat recurrent oral ulcer was 98.8%.Conclusion:Compound ofloxacin film can be pr- pared easily.The film is reliable curative effect and salty.
Keywords:ofloxacin  tetracaine hydrochloride  film  chitosan  observation of clinical effect
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