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毛大丁草根和根茎化学成分的研究
引用本文:肖瑛,李建北,丁怡. 毛大丁草根和根茎化学成分的研究[J]. 中国中药杂志, 2002, 27(8): 594-596
作者姓名:肖瑛  李建北  丁怡
作者单位:中国医学科学院,中国协和医科大学,药物研究所,北京,100050
基金项目:北京市科委 2 48生物医药基地项目 (95 5 0 2 14 90 0 )
摘    要:目的 :研究毛大丁草根和根茎的化学成分。方法 :采用硅胶柱色谱法分离纯化 ,薄层色谱及光谱法进行结构鉴定。结果 :从其乙醇提取物的乙酸乙酯萃取部分分得 7个化合物 ,其结构鉴定为bothrioclinin (Ⅰ) ,氢醌(Ⅱ) ,异紫花前胡内酯 (Ⅲ) ,琥珀酸 (Ⅳ) ,伞形花内酯 (Ⅴ) ,isoarborinol (Ⅵ) ,β-谷甾醇 (Ⅶ)。 结论 :化合物Ⅰ ,Ⅴ ,Ⅵ为首次从该属植物中分离得到。

关 键 词:菊科  大丁草属  毛大丁草  化学成分
文章编号:1001-5302(2002)08-0594-03
收稿时间:2001-01-18
修稿时间:2001-01-18

Studies on the Chemical Constituents from the Roots and Rhizomes of Gerbera piloselloides
XAO Ying;LI Jian bei;DING Yi. Studies on the Chemical Constituents from the Roots and Rhizomes of Gerbera piloselloides[J]. China Journal of Chinese Materia Medica, 2002, 27(8): 594-596
Authors:XAO Ying  LI Jian bei  DING Yi
Affiliation:Institute of Materia Medica, Chinese Academy of Medical Sciences, Beijing 100050, China.
Abstract:OBJECTIVE: To study the chemical constituents from the roots and rhizomes of Gerbera piloselloides. METHOD: The compounds were isolated by silica gel column chromatography, and their structures were elucidated by means of spectral analysis. RESULT: Seven compounds were identified as bothrioclinin (I), hydroquinone (II), marmesin (III), succinic acid (IV), umbelliferone (V), isoarborinol (VI) and beta-sitosterol (VII). CONCLUSION: Compound I, V and VI were isolated from Gerbera genus for the first time.
Keywords:compositae  Gerbera genus  Gerbera piloselloides  chemical constituents
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