不同人群冠状动脉病变增龄性对比研究

目的:探讨军人与非军人冠心病(coronary heart disease,CHD)的危险因素及流行病学特征,评价增龄、职业差异与CHD的相关性。方法:入选军人临床拟诊冠心病患者221例,非军人临床拟诊冠心病患者1 060例,按军人和非军人及年龄分组,进行冠状动脉病变、危险因素分析。结果:军人和非军人冠心病组年龄差异有统计学意义(P<0.001),两组病变危险因素,累及血管支数、病变部位、Gensini积分差异无统计学意义(P>0.05)。军人和非军人中随着年龄增长,Gensini总积分逐渐增加,非军人70～岁年龄段Gensini总积分与军人80～岁组相比差异无统计学意义(P>0.05)。结论:随着增龄,冠脉病变程度逐渐加重。在相同危险因素、相同动脉粥样硬化病变程度,非军人比军人年龄提前10岁左右,提示除传统危险因素外,社会生活环境、不同职业水平也是冠心病的危险因素。

A comparison study of aging coronary artery lesion among different occupation groups

Objective: To investigate risk factors and epidemic character of coronary heart disease(CHD)in servicemen and non-servicemen,and to evaluate the relationship between CHD and aging,occupation.Methods:A total of 221 servicemen and the 1 060 non-servicemen with preliminary diagnosis of CHD were selected,and grouped according to the age.Risk factors were analyzed.Results:There was significant difference in age(P<0.001),and no significant difference in risk factor,the number of involving blood vessels,lesion location,or Gensini score(P>0.05).With the increase of age,total Gensini score of servicemen and non-servicemen gradually increased,and there was no significant difference in total Gensini score between non-servicemen aged 70 years old and servicemen aged 80 years old(P>0.05).Conclusions:As aging,degree of coronary artery disease will become more serious.With the same risk factors and the same degree of atherosclerotic lesions,the age of non-service man patient is about 5 years old younger than service-man patient,suggesting that in addition to traditional risk factors,social environment,different occupation also contribute to coronary heart disease.