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Granulomatous hepatitis after intravesical BCG treatment for bladder cancer.
Authors:Osman Ersoy  Rasit Aran  Musa Aydinli  Ozlem Yonem  Ozgur Harmanci  Bulent Akdogan  Ahmet Pinar  Cenk Sokmensuer  Yusuf Bayraktar
Institution:Department of Gastroenterology, Hacettepe University Faculty of Medicine, Ankara, Turkey. roersoy@tnn.net
Abstract:Intravesical bacillus Calmette-Guerin (BCG) is used in patients with urinary bladder carcinoma. Although it is generally well tolerated, granulomatous hepatitis is a rare but serious complication. We report a 42-year-old man and a 56-year-old man who developed granulomatous hepatitis following intravesical BCG. One of them was treated successfully with antitubercular therapy; the other died because of BCG sepsis and multi-organ failure.
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