Estrogen and progesterone binding sites in renal cell carcinoma |
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Authors: | W L Orovan E D Ryan |
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Institution: | Department of Pathology, McMaster University, Hamilton, Ontario, Canada. |
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Abstract: | Twenty-five renal cell carcinomas were assayed for estrogen and progesterone receptor levels. Estrogen specific binding was present in only 4 patients (16%) and progesterone specific binding in 7 patients (28%). In all cases these receptors were present in very low titers, less than 10 fm/mg. We believe that earlier reports citing significant estrogen and progesterone binding activity may reflect high levels of nonspecific protein binding. |
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