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185例常年变应性鼻炎患者的吸入性过敏原分析
引用本文:曾文,罗福东,曾丽,闵玲,麦荣嘉. 185例常年变应性鼻炎患者的吸入性过敏原分析[J]. 中国妇幼卫生杂志, 2013, 0(1): 20-21
作者姓名:曾文  罗福东  曾丽  闵玲  麦荣嘉
作者单位:广东省妇幼保健院检验科;广东省中医院检验科
摘    要:目的探讨常年变应性鼻炎患者吸入性过敏原的分布情况,为变应性鼻炎的防治提供依据。方法采用免疫印迹方法定量检测185例常年变应性鼻炎患者血清中7种常见吸入性过敏原的IgE抗体,并对过敏原分布进行统计分析。结果 185例常年变应性鼻炎患者血清中,过敏原以户尘螨阳性率最高(80%),其次是蟑螂(43.8%)和猫狗皮屑(31.9%)。男女性别组间过敏原阳性率差异无统计学意义(P〉0.05)。各年龄段均有检出,但以中青年患者居多。结论户尘螨是诱导该185例常年性变应性鼻炎病例的主要吸入性过敏原。

关 键 词:常年性变应性鼻炎  IgE抗体  吸入性过敏原

Clinical characteristics of inhalational allergen in 185 perennial allergic rhinitis patients in Guangzhou
ZENG Wen,LUO Fu-dong,ZENG Li,MIN Ling,MAI Rong-jia. Clinical characteristics of inhalational allergen in 185 perennial allergic rhinitis patients in Guangzhou[J]. Chinese Journal of Women and Children Health, 2013, 0(1): 20-21
Authors:ZENG Wen  LUO Fu-dong  ZENG Li  MIN Ling  MAI Rong-jia
Affiliation:1 (1.Guangdong Women and Children Hospital,Guangzhou, Guangdong 510000,P.R.China;2.Guangdong Traditional Chinese Medicine Hospital, Guangzhou, Guangdong 510000,P.R.China)
Abstract:[ Objective ] To detect common inhalational allergen in patients with perennial allergic rhinitis who go to our hospital and provide a scientific basis for clinical diagnosis and treatment. [ Methods ] Immunoblot was used to detect IgE antibody against seven kinds of anaphylactogen in patients' serum.The distribution of anaphylactogen was analyzed by statistical methods. [ Resluts ] The major allergen inducing perennial allergic was followed by cockroach (43.8%) and dandruff of cat and dog (31.9%).There was no Dermatophagoides pteronyssinus (80%), significant statistical difference between the sexes (P〉0.05).All ages could suffer from the disease, but there were mostly middle-aged patients. [ Conclusion ] Dermatophagoides pteronyssinus is the main inhalational allergen which is responsible for PAR in these investigation cases
Keywords:perennial allergic rhinitis(PAR)  IgE antibody  inhalational allergen
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