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Electrolyte disturbance with omeprazole therapy
Authors:C. Melville  A. Shah  D. Matthew  P. Milla
Affiliation:(1) Department of Paediatric Gastroenterology, The Hospital for Sick Children, Great Ormond Street, WC1 London, UK;(2) Department of Intensive Care, The Hospital for Sick Children, Great Ormond Street, WC1 London, UK
Abstract:Omeprazole is an antagonist to the H+K+ ATPase of the gastric parietal cell. We report a case of severe electrolyte disturbance in a 5-year-old child treated with omeprazole associated with excessive urinary sodium loss, that responded completely to omeprazole with-drawal.
Keywords:Proton pump inhibitor Omeprazole  Oesophagitis  Electrolyte disturbance  Bartter's syndrome  Congenital chloridorrhoea
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