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Prone position and pressure control inverse ratio ventilation in H1N1 patients with severe acute respiratory distress syndrome
Authors:Pradeep M. Venkategowda  S. Manimala Rao  Yogesh R. Harde  Mithilesh K. Raut  Dnyaneshwar P. Mutkule  Kartik Munta  Mallela V. Rao
Affiliation:From: Department of Critical Care Medicine, Yashoda Multi-speciality Hospital, Somajiguda, Hyderabad, Telangana, India;1Department of General Medicine, Yashoda Multi-speciality Hospital, Somajiguda, Hyderabad, Telangana, India
Abstract:Aim:To observe the 28 and 90 days mortality associated with prone position and assist control-pressure control (with inverse ratio) ventilation (ACPC-IRV).Results:At admission, among these six patients the mean tidal volume generated was about 376.6 ml which was in the range of 6–8 ml/kg predicted body weight. The mean lung injury score was 3.79, mean PaO2 /FiO2 ratio was 52.66 and mean oxygenation index was 29.83. The mean duration of ventilation was 9.4 days (225.6 h). The ICU length of stay was 11.16 days. There was no mortality at 28 and 90 days.Conclusion:Early prone combined with ACPC-IRV in H1N1 patients having severe ARDS can be used as a rescue therapy and it should be confirmed by large observational studies.
Keywords:Influenza A virus   inverse ratio ventilation   pressure control ventilation   prone position   severe acute respiratory distress syndrome
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