| 正交试验法优选湘A-2号颗粒水提工艺的研究 |
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| 引用本文： | 蒋敏,夏新华.正交试验法优选湘A-2号颗粒水提工艺的研究[J].中国民族民间医药杂志,2009,18(6). |
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| 作者姓名： | 蒋敏 夏新华 |
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| 作者单位： | [1]湖南省医药学校,湖南长沙410014 [2]湖南中医药大学,湖南长沙410208 |
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| 基金项目： | 湖南省卫生厅中医药科研专项基金(6201-5) |
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| 摘 要： | 目的 优选水提湘A-2号的提取工艺。方法：以芍药苷含量、浸膏得率为评价指标，高效液相色谱法定量。采用正交设计试验法，探讨水提湘A-2号的浸泡时间（A）、加水量（B）、提取时间（C）等最优工艺参数。结果：水提最佳提取工艺条件为浸泡时间0．5h、加水量分别为12倍量和10倍量、提取时间分别为2．5h和2．0h。结论：该提取工艺稳定可行，适合于工业化生产，为湘A-2号颗粒制剂的研究奠定基础。
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| 关 键 词： | 湘A-2号颗粒 水提 芍药苷 正交试验 高效液相法 |
Study on water extraction for Xiang A-2 Granules by orthogonal design |
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| JIANG min,XIA Xin-hua.Study on water extraction for Xiang A-2 Granules by orthogonal design[J].Chinese Journal of Ethnomedicine and Ethnopharmacy,2009,18(6). |
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| Authors: | JIANG min XIA Xin-hua |
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| Institution: | 1.The hunan school of medicine and pharmacy;Changsha;hunan;410014;2.Hunan University of TCM;410208 |
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| Abstract: | Objective:To optimize the conditions of water extraction for Xiang A-2 Granules.Methods:Using the content of paeoniflorin,extraction rate as the index,HPLC was used to quantitative,soaking time(A),the amout of water(B),extracting time(C),degree on extraction technology were evaluated by orthogoral design method.Results:The superior technology of water extraction were as follow:soaking in water for 0.5 h,12 times and 10 times as much water,extracted 2.5 h and 2 h.Conclusion:The extraction technology was stab... |
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| Keywords: | Xiang A-2 Granules water extraction paeoniflorin orthogonal design HPLC |
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