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Detection of incompletely sialylated human chorionic gonadotropin by peanut agglutinin in choriocarcinoma |
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| Authors: | R Nishimura T Mizuochi T Utsunomiya K Ide A Kobata M Mochizuki |
| Abstract: | Human chorionic gonadotropin (hCG) in normal pregnancy and hydatidiform mole did not bind to the peanut agglutinin (PNA)-Sepharose column, whereas significant amount of hCG in choriocarcinoma adsorbed to the column. Therefore, PNA-Sepharose affinity chromatography is an effective tool for the detection of desialylated hCG and may be useful also for the diagnosis of choriocarcinoma. |
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