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抗独特型抗体在寄生虫病领域的研究进展及应用
引用本文:许静,冯振卿,管晓虹.抗独特型抗体在寄生虫病领域的研究进展及应用[J].国际医学寄生虫病杂志,2008,36(1):167-172.
作者姓名:许静  冯振卿  管晓虹
作者单位:210029,南京医科大学卫生部抗体技术重点实验室;200025,上海,中国疾病预防控制中心寄牛虫病预防控制所血吸虫病室;南京医科大学卫生部抗体技术重点实验室,210029;
基金项目:国家高技术研究发展计划(863计划)
摘    要:独特型及抗独特型抗体源自免疫网络学说,抗独特型抗体具有模拟抗原及免疫调节的作用.基于这一理论基础,抗独特型抗体已被J一泛应用于疾病的免疫诊断、疫苗及免疫治疗等方面的研究中.该义就抗独特型抗体的制备、鉴定方法以及其在寄生虫病领域中的研究进展进行综述.

关 键 词:抗独特型抗体    诊断    疫苗    免疫治疗    寄生虫    

Research progress on anti-idiotype antibody and its application in parasitic diseases
XU Jing,FENG Zhen-qing,GUAN Xiao-hong.Research progress on anti-idiotype antibody and its application in parasitic diseases[J].International JOurnal of Medical Parasitic Diseases,2008,36(1):167-172.
Authors:XU Jing  FENG Zhen-qing  GUAN Xiao-hong
Abstract:Idiotype and anti-idiotype antibody were put forward in the theory of immune network.Based on the concept that anti-idiotype antibody exhibits the characteristics with antigen imitation and immune modulation,it has been widely used in immunodiagnosis,vaccine and immunotherapy of diseases.In this review,the progress Oil production,characterization of anti-idiotype antibody and its application in parasitic diseases were summarized.
Keywords:Anti-idiotype antibodyDiagnosisVaccineImmunotherapyParasite
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