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消咳宁片质量标准的研究
引用本文:倪萍. 消咳宁片质量标准的研究[J]. 中国医药导报, 2008, 5(30): 38-39
作者姓名:倪萍
作者单位:江苏省盐城药品检验所,江苏盐城,224002
摘    要:目的:建立消咳宁片的质量标准。方法:采用TLC法对处方中甘草浸膏进行鉴别,采用HPLC法测定盐酸麻黄碱的含量。结果:TLC鉴别方法分离度好,专属性强,盐酸麻黄碱在4.476~15.666μg/ml范围内线性关系良好(r=0.9995),平均回收率为96.66%,RSD=1.36%(n=6)。结论:所建立的质量标准评价方法准确、可靠、便捷、专属性强,可有效控制消咳宁片的质量。

关 键 词:消咳宁片  盐酸麻黄碱  TLC  HPLC

Study on quality standard for Xiaokening Tablets
NI Ping. Study on quality standard for Xiaokening Tablets[J]. China Medical Herald, 2008, 5(30): 38-39
Authors:NI Ping
Affiliation:NI Ping (Yancheng Institute for Drug Control,Jiangsu Province,Yancheng 224002,China)
Abstract:Objective:To establish the quality standard for Xiaokening Tablets. Methods:Glycyrrhiza extract in Xiaokening Tablets were identified by TLC.The Content of Ephedrine hydrochloride was determined by HPLC. Results :The identification by TLC was distict and highly specific. Ephedrine hydrochloride had a good linear relationship at the range of 4.476- 15.666 μg/ml, the average ecovery was 96.66%,RSD was 1.36%(n=6). Conclusion:The method is reliable,accurate and specific, and can be used for the quality control of Xiaokening Tablets.
Keywords:TLC  HPLC
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