胃肠道间质瘤18例临床分析

目的：探讨胃肠道间质瘤的诊断与治疗。方法：对18例胃肠道间质瘤的临床资料及诊断、治疗结果进行回顾性分析。结果：18例胃肠道间质瘤患者术前均未获明确诊断，均有腹痛、黑便症状，其中消化道大出血6例，腹部包块6例，幽门梗阻3例,合并穿孔1例。发病部位：胃部16例中1例失去手术机会，余15例均手术治疗；空肠2例为术中探查发现。术后随访15例，随访率为83．3％，1、3、5年生存率分别为93．3％、66．7％、46．7％。结论：胃肠道间质瘤术前诊断较困难，术中应常规仔细探查空肠近端，谨防漏诊，完全彻底切除，预后较好。

Clinical analysis of 18 cases with gastrointestinal stromal tumors

Objective: To investigate the diagnosis and therapy of gastrointestinal stromal tumor (GIST). Methods: The clinical data of 18 patiens with GIST were analysed retrospectively. Results: In 18 patiens, the diagnosis rate preoperatively was 0, among them, 18 cases had hematemesis and melanorragia; 6 gastroenteric hemorrhage; 4 abdominal mass; 3 cases pylorochesis; and 1 perforation. Location of the lesion: 14 cases in stomach, among them, 1 cases had lost chance of opration,the rest all were oprated; 2 cases in jejunum, they were found by explortion in operation. 15 patiens (83.3%) have been followed up, the postoperative 1, 3, 5 year survival rates were 93.3%, 66.7%, 46.7% respectively. Conclusions: The dianosis of GIST is diffcult, which shoud be pay more attention before operation.Operator shoud explore near jejunum in routine, preventing from off dignosis. If thoroughly radical resection, its prognosis will be better