单精子胞质内注射治疗严重男性不育和受精障碍102个周期的回顾性分析

回顾性分析从 1 998年 1月至 2 0 0 0年 1 2月在我室接受单精子显微授精治疗的共 1 0 2个周期。以 2 0 0 0年2月为界 ,随着显微操作技术 ,的改进和操作环境的改善 ,后阶段单精子显微注射的存活率 (90 6 % )、受精率 (73 3 % )、胚胎发育率 (97 3 % )较前阶段 (分别为 68 8% ,39 0 % ,78 7% )有显著提高。两阶段临床妊娠率分别为 41 3 %和2 1 4% ,目前本室建立的单精子胞质内注射技术能有效地治疗临床严重男性不育和受精障碍

trospective analysis of 102 cycles of intracytoplasmic single sperm injection in treating severe male infertility and fertilization failure

The aim of this study is to retrospectively analyze 102 cycles which received intracytoplasmic single sperm injection (ICSI) in our lab from January 1998 to December 2000. With the improvements of the technique and environment of the microscopic manipulation from February 2000, the survival rate (90.6%). fertilization rate (73.3%) and embryo development rate (97.3%) of the later stage were significantly higher than those of the previous (68.8%, 39.0%, 78.7% respectively). The clinical pregnancy rate reached a higher level (41.3% and 21.4% respectively). The ICSI technique established currently in our lab can effectively treat the severe male infertility and fertilization failure.