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| 氟喹诺酮类抗菌药物耐药性与耐药机制的研究进展 | |
| 引用本文： | 罗景慧,刘永刚,杨西晓,候连兵,杨迎暴. 氟喹诺酮类抗菌药物耐药性与耐药机制的研究进展[J]. 抗感染药学, 2013, 10(2): 86-91 |
| 作者姓名： | 罗景慧 刘永刚 杨西晓 候连兵 杨迎暴 |
| 作者单位： | 1. 南方医院药学部,广州,510515 2. 武警广东总队医院药剂科,广州,510507 3. 南方医科大学药学院临床药理研究室,广州,510515 |
| 摘 要： | 目前,喹诺酮类药物（nuoroquinolones,FQs）是临床最常用的人工合成抗茵药物;但是,在抗茵药的选择压力下,临床常见致病菌对FQs耐药问题目渐严重。利用PubMed和CNKI两大数据库平台,检索2011—2012年期间发表的FQs耐药流行病学、耐药机制和有效对策的文献,对其研究进展作一综述,并对有效防控FQs耐药性提出相应对策措施。 |
| 关 键 词： | 氟喹诺酮类 耐药性 耐药机制 |
Recent Advances in Evaluation of Resistance Epidemiology and Mechanisms of Fluoroquinolone |
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| LUO Jing-hui , LIU Yong-gan , YANG Xi-xiao , HOU Lian-bing , YANG Ying-bao. Recent Advances in Evaluation of Resistance Epidemiology and Mechanisms of Fluoroquinolone[J]. Anti-infection Pharmacy, 2013, 10(2): 86-91 | |
| Authors: | LUO Jing-hui LIU Yong-gan YANG Xi-xiao HOU Lian-bing YANG Ying-bao |
| Affiliation: | 1 Department of Pharmacy, Nanfang Hospital, Guangzhou 510515, China; 2Department of Pharmacy, Guangdong Province Corps Hospital, Chinese People＇s Army Force, Guangzhou 510507, China,＂ 3School of Pharmaceutical Sciences, Southern Medical University, Guangzhou 510515, China |
| Abstract: | Fluoroquinolones（FQs）are the most widely used synthetic antibacterial drugs in the clinical. However, FQs have been acquiring more and more resistance in the common pathogens in the clinical practice because of the selective pressure. Based on two large data bases, PubMed and CNKI, the research literatures involving the advances of FQs-resistant epidemiology, mechanisms and anti-resistance strategies published between 2011 and 2012 were retrieved and reviewed. In the meantime, and the effective procedures to prevent FQs resistance were discussed. |
| Keywords: | fluoroquinolones resistance resistance mechanisms |
| 本文献已被 维普 万方数据 等数据库收录！ | |