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严重烧伤后渗透分子清除率和自由水清除率变化及其临床意义
引用本文:刘德贵,杨勋忠,吴其林,杨宗诚,黎鳌.严重烧伤后渗透分子清除率和自由水清除率变化及其临床意义[J].西南国防医药,1994(5).
作者姓名:刘德贵  杨勋忠  吴其林  杨宗诚  黎鳌
作者单位:成都军区总医院烧伤整形科 610083 (刘德贵,杨勋忠,吴其林),第三军区大学西南医院烧伤研究所 630038 (杨宗诚),第三军区大学西南医院烧伤研究所 630038(黎鳌)
摘    要:本文测定了59例不同烧伤面积病人血、尿晶体渗透压,计算渗透分子清除率(Cosm)和自由水清除率(C_(H_2O))并进行了动态观察。结果发现随着烧伤面积增加,血晶渗压(Posm)和C_(H_2O)升高,而尿晶渗压(Uosm)和Cosm下降,尤以TBSA>80%组变化最为显著,ARF组较non—ARF变化明显。死亡病人生前Posm、C_(H_2O)明显高于而Uosm、Cosm明显低于存活病人,且Posm、C_(H_2O)增加与Uosm、C_(H_2O)降低往往同时存在。测定Posm、Uosm、Cosm、C_(H_2O)对严重烧伤后肾功能损害监测、判定病情及估计预后均有积极的指导意义

关 键 词:烧伤  肾功能损害  渗透分子清除率  自由水清除率  肾功能试验

CHANGES OF CLEARANCES OF Osmole AND FREE WATER IN BURN PATIENTS AND THEIR CLINICAL SIGNIFICANCE
Liu Degui,Yang Xunzhong,Wu Qiling. Yang Zongcheng. Li Ao.CHANGES OF CLEARANCES OF Osmole AND FREE WATER IN BURN PATIENTS AND THEIR CLINICAL SIGNIFICANCE[J].Medical Journal of National Defending forces in Southwest China,1994(5).
Authors:Liu Degui  Yang Xunzhong  Wu Qiling Yang Zongcheng Li Ao
Institution:Liu Degui,Yang Xunzhong,Wu Qiling. Yang Zongcheng. Li Ao Department of Burn and Plastic Surgery,General Hospital of Chengdu Military Command.
Abstract:The plasma and urine osmolality and clearances of osmole (Cosm) and free water (Cn,o) in 59 burn patients were determined with freezing point depressing method. The results showed that there were significant increases of Posm and CH2O and decreases of Uosm and Cosm in the burn patients, which correlated positively to the extents of the burn injury as well as the severity of renal damage. The Cosm significantly decreased and CH2O increased before the death. The findings suggested that the determination of Posm, Uosm, Cosm and CH2O might be helpful to understanding postburn renal damage and severity of the burn injury and evaluating the prognosis of the injury.
Keywords:burn  renal damage  renal function test  clearance of osmole  
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