| 绞股蓝总皂甙对氧自由基所致脑血管痉挛的保护作用 |
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| 引用本文： | 陈剑雄,廖端芳,唐小卿,余麟,曾恒,曹建国.绞股蓝总皂甙对氧自由基所致脑血管痉挛的保护作用[J].中草药,1997,28(4):219-221. |
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| 作者姓名： | 陈剑雄 廖端芳 唐小卿 余麟 曾恒 曹建国 |
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| 作者单位： | 衡阳医学院药理教研室!421001(陈剑雄，廖端芳，唐小卿，余麟，曹建国)，衡阳医学院附一院(曾恒) |
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| 摘 要： | 研究绞股蓝总皂甙（GPS）对外源性氧自由基所致家兔脑基底动脑损伤的保护作用，外源性氧自由基由电解克氏液产生，电解后，脑基底动脉灌注压及血管壁丙二醛（MDA）含量明显升高，脑基底动脉内皮舒张作用，亚硝酸盐及超氧化物歧化酶（SOD）活性明显降低，GPS25、50、100μg／mL可浓度依赖性地抑制氧自由基诱发脑血管收缩作用，此外GPS100μg／mL还具有明显抑制血管壁MDA生成，保护SOD活性的作用。
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| 关 键 词： | 绞股蓝总皂甙 电解 氧自由基 基底动脉 |
| 收稿时间： | 1995/12/4 0:00:00 |
Protection of Gypenoside Against Oxygen Free Radical Induced Vasospasm of Isolated Rabbit Basilar Artery |
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| Chen Jianxiong,Liao Duan fang,Tang Xiaoqing.Protection of Gypenoside Against Oxygen Free Radical Induced Vasospasm of Isolated Rabbit Basilar Artery[J].Chinese Traditional and Herbal Drugs,1997,28(4):219-221. |
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| Authors: | Chen Jianxiong Liao Duan fang Tang Xiaoqing |
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| Institution: | Department of Pharmacology, Hengyang Medical College, Hengyang;Department of Pharmacology, Hengyang Medical College, Hengyang;Department of Pharmacology, Hengyang Medical College, Hengyang;Department of Pharmacology, Hengyang Medical College, Hengyang;Department of Pharmacology, Hengyang Medical College, Hengyang;Department of Pharmacology, Hengyang Medical College, Hengyang |
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