A comparison of immunochemical methods for the detection of antibodies to myelin encephalitogenic protein. |
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Authors: | J N Whitaker D E McFarlin |
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Affiliation: | 1. Department of Psychology, Emory University, Atlanta, Ga. 30322, USA;2. Department of Psychology, The University of Iowa, Iowa City, Iowa 52242 U.S.A. |
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Abstract: | The antibody titer to myelin encephalitogenic protein in rabbits and rats has been comparatively studied by double antibody radioimmunoassay, quantitative microcomplement fixation, and radioimmunoelectrophoresis. In general, these immunochemical tests quantitatively paralleled one another but minor differences were sometimes present. The desirability of using a combination of these methods in assesing the antibody response to myelin encephalitogenic protein is emphasized. |
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Keywords: | Please direct all correspondence and requests for reprints to: Dr. David M. Jacobowitz Laboratory of Clinical Science Building 10/Room 2D-46 National Institute of Mental Health Bethesda Md. 20014 U.S.A. |
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