巨大儿青少年期血糖、血脂和转氨酶水平的调查研究

目的研究巨大儿至青少年期血糖、血脂和转氨酶的代谢变化,以了解巨大儿与成人代谢综合征的相关性。方法选取出生时体质量大于或等于4000 g的巨大儿,年龄13~18岁的青少年148例为研究对象,按1∶1选取配对的148例为对照组,测定血糖、血脂和转氨酶的含量,并比较两组间的差异。结果巨大儿组的空腹血糖及转氨酶水平明显高于对照组,差异有统计学意义(P0.05),对动脉硬化有保护作用的高密度脂蛋白胆固醇(HDL-C)的含量明显低于对照组,差异有统计学意义(P0.05)。结论出生体质量与青少年相关代谢紊乱关系密切。

Study on levels of blood glucose, blood lipids, transaminase of macrosomia in adolescents

Objective To investigate the metabolic change of levels of blood glucose,blood lipids,transaminase of macrosomia in adolescents, and to realize the relationship of macrosomia and metabolic syndrome in adults. Methods 148 adolescent cases with weight ≥4 kg macrosomia and aged between 13- 18 years old were selected,and meanwhile 148 control cases were selected for studying objects by one to one contrast. The levels of blood glucose, blood lipid and transaminase were assayed. To compare the difference between the two groups. Results The levels of blood glucose and transaminase of macrosomia group were significantly higher than those of the control group（P〈0.05）, but the content of HDL C with a protective effect on atherosclerosis was significantly lower than that of the control group（P〈0.05）. Conclusion There is close relation in the body weight at birth and metabolic disorders in adoles- cent stage.