Multiple Pseudopolyps Presenting as Reddish Nodules Are a Characteristic Endoscopic Finding in Patients with Early-stage Autoimmune Gastritis |
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Authors: | Tohru Kotera Keishi Oe Ryoji Kushima Ken Haruma |
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Affiliation: | 1.Department of Medical Examination, Uji-Tokushukai Medical Center, Japan; 2.Department of Emergency and General Medicine, Uji-Tokushukai Medical Center, Japan; 3.Department of Pathology, Shiga University of Medical Science, Japan; 4.Department of General Internal Medicine 2, Kawasaki Medical School General Medical Center, Japan |
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Abstract: | We herein report two cases of autoimmune gastritis without complete atrophy of the corpus. Both were positive for anti-parietal cell antibodies. Endoscopic examinations indicated that atrophic changes were predominant in the lesser curvature of the corpus in both cases. In one, the greater curvature was covered with pseudopolyp-like nodules, whereas the greater curvature of the other showed multiple similar nodules and mildly atrophic mucosa. Histopathological examinations of these nodules showed focal and patchy atrophy and preserved fundic glands with parietal cell pseudohypertrophy. Follow-up endoscopy and a repeated biopsy demonstrated the development of gastric atrophy on the greater curvature in both cases. |
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Keywords: | autoimmune gastritis anti-parietal cell antibody gastric pseudopolyp parietal cell pseudohypertrophy |
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