C-Reactive Protein,Fibrinogen, Leptin,and Adiponectin Levels in Women with Polycystic Ovary Syndrome |
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| Authors: | Cagdas Ozgokce Erkan Elci Recep Yildizhan |
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| Affiliation: | 1.Department of Obstetrics and Gynecology, Private Van Akdamar Hospital, Van, Turkey ;2.Department of Obstetrics and Gynecology, University of Healty Sciences Umraniye Training and Research Hospital, Istanbul, Turkey ;3.Department of Perinatology, Demiroglu Bilim University Faculty of Medicine, Abide-I Hürriyet Street, No: 164, Şişli, Istanbul, Turkey |
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| Abstract: | Background and AimWe aimed to compare the levels of clinical, biochemical, hormonal, and metabolic parameters as well as serum CRP, fibrinogen, leptin, and adiponectin in cases with PCOS and control group to investigate whether they play a role in the etiology of the syndrome.Materials and MethodsThe present study included a total of 90 subjects, 45 subjects were diagnosed with PCOS (n = 45) and 45 subjects served as control group (n = 45). Serum CRP, fibrinogen, leptin, and adiponectin levels were analyzed for each subject.ResultsSerum CRP, fibrinogen, and leptin were found to be higher (statistically significant) in the group with PCOS as compared to the control group (p < 0.05). Serum Adiponectin was higher in the control group (statistically significantly) as compared with the patients in the PCOS group (p < 0.05).ConclusionCRP and fibrinogen (cardiac risk factor markers) increase in women with PCOS. The levels of leptin which affects metabolism increase, whereas the levels of adiponectin decrease. |
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| Keywords: | PCOS CRP Leptin Adiponectin Fibrinogen |
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