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富硒枸杞抗肾脏衰老作用的形态学定量研究
引用本文:刘晓梅,李伟安,王景霞,佟春玲. 富硒枸杞抗肾脏衰老作用的形态学定量研究[J]. 黑龙江医药科学, 2005, 28(5): 22-23
作者姓名:刘晓梅  李伟安  王景霞  佟春玲
作者单位:佳木斯大学基础医学院组胚教研室 黑龙江佳木斯154007(刘晓梅,王景霞),佳木斯市中心医院 黑龙江佳木斯154002(李伟安),佳木斯大学基础医学院组胚教研室 黑龙江佳木斯154007(佟春玲)
摘    要:目的:探讨富硒枸杞抗肾脏衰老的作用。方法:建立小鼠衰老模型,以10%富硒枸杞水煎剂连续灌胃42d,采用光镜,透射电镜,组织化学和B I2000图象分析系统对小鼠肾脏各项形态学指标进行定量分析。结果:富硒枸杞实验组肾小球形态大小,肾小球硬化率,肾组织内微血管指标,肾小球平均细胞数,肾小球基底膜厚度均较老年对照组有显著性差异(P<0.05或P<0.01)。结论:富硒枸杞具有较好的预防或延缓小鼠肾脏衰老的作用。

关 键 词:富硒枸杞  肾脏  抗衰老  形态定量分析
文章编号:1008-0104-(2005)05-0022-02
修稿时间:2005-09-15

Anti-aging effects of Seleniferous Lycium Barbarum L on the kidney: Morphologic studies
LIU Xiao-mei,LI Wei-an,WANG Jing-xia,TONG Chun-ling. Anti-aging effects of Seleniferous Lycium Barbarum L on the kidney: Morphologic studies[J]. Heilongjiang Medicine and Pharmacy, 2005, 28(5): 22-23
Authors:LIU Xiao-mei  LI Wei-an  WANG Jing-xia  TONG Chun-ling
Affiliation:LIU Xiao-mei~1,LI Wei-an~2,WANG Jing-xia~1,TONG Chun-ling~1
Abstract:Objective: To investigate the anti-aging effect of Seleniferous Lycium barbarum L on the kidney.Methods: The model of aging mouse was prepared and the apozeme of 10% Seleniferious Lycium Barbarum L was poured into the mouse stomach for 42d.The quantitative analysis was made of the morphologic indexes of the mouse kidney by light microscopy,TEM,histochemistry method and BI2000 image analysis system.Results: There were significant differences in the glomcrulus shape-size,glomerular sclerosis rate,nephridial tissue micrangium indexes,average renal glomerular cell number and renal glomerular basement membrane thickness between the Seleniferous Lycium Barbarum L group and the aged control group(P<0.05 or P<0.01). Conclusion: Seleiferous Lycium Barbarum L has better anti-aging effects on the mouse kidney.
Keywords:Seleniferious Lycium Barbarum L  kidney  anti-aging  morphous quantitive analysis
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