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环氧乙烷对小鼠脊髓神经细胞膜上嵌入蛋白质分布的影响
引用本文:陈光忠,夏国兴,陆静芬,钟坤,张龄.环氧乙烷对小鼠脊髓神经细胞膜上嵌入蛋白质分布的影响[J].解剖学杂志,2000,23(1):87-89.
作者姓名:陈光忠  夏国兴  陆静芬  钟坤  张龄
作者单位:上海职工医学院解剖学教研室,上海,200237
基金项目:国家自然科学基金资助(编号39070477)
摘    要:目的:研究环氧乙烷对小鼠神经细胞膜上嵌入蛋白质分布的影响。方法:小鼠每天吸入环氧乙烷2h,持继2或3个月,用冰冻蚀刻电镜观察小鼠腰髓前角神经细胞膜上嵌入蛋白质的 分布。结果:随着染毒时间延长,腰髓前肴神经细胞膜上的嵌入蛋白质由分布紊乱至成簇聚集。结论:环氧乙烷能改变神经细胞膜上嵌入蛋白质的分布。

关 键 词:脊髓  神经细胞  细胞膜  嵌入蛋白质  环氧乙烷

Effects of Ethlene Oxide on Distribution of Inserting Protein on Nerve Cell Membrane of Spinal in Mice
Chen Guangzhong,Xia Guoaxin,Lu Jingfen,Zhong Kun,Zhang Ling.Effects of Ethlene Oxide on Distribution of Inserting Protein on Nerve Cell Membrane of Spinal in Mice[J].Chinese Journal of Anatomy,2000,23(1):87-89.
Authors:Chen Guangzhong  Xia Guoaxin  Lu Jingfen  Zhong Kun  Zhang Ling
Abstract:To study effects of ethylene oxide on the distribution of inserting proteins in nerve cell membrane of mice. Methods: The mice were inhaled ethylene oxide for 2 hours every day. After 2 or 3 months, scanning electron microscope with freeze etching was used to observe the distribution of inserting proteins in nerve cell membrane of anterior horn in spinal cord of mice. Results: as the extending of inhaling time inserting proteins distribution changed from turbulence to cluster. Conclusion: Ethylene oxide can change the distribution of inserting proteins in nerve cell membrane.
Keywords:spinal cord  nerve cell  cell membrane  inserting proteins  ethylene oxide
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