Risk of Clostridium difficile-associated disease among patients receiving proton-pump inhibitors in a Quebec medical intensive care unit. |
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| Authors: | Mathieu Beaulieu David Williamson Gilbert Pichette Jean Lachaine |
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| Affiliation: | Faculty of Pharmacy, Universite de Montreal, Montreal, QC, H3C 3J7, Canada. mathieu.beaulieu@umontreal.ca |
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| Abstract: | Our study was conducted to determine whether use of gastric acid-suppressive agents increased the risk of Clostridium difficile-associated disease (CDAD) in a medical intensive care unit of one of the first hospitals to be threatened by the current CDAD epidemic in Quebec, Canada. Our findings suggest that efforts to determine risk factors for CDAD should focus on other areas, such as older age and antibiotic use. |
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