中国成年人饮茶与死亡风险的前瞻性关联研究

目的分析中国成年人饮茶与全因死亡和死因别死亡风险间的关联。方法本研究分析基于中国慢性病前瞻性研究项目。饮茶信息为基线自报。死亡信息主要通过链接死亡监测系统获取。使用Cox比例风险回归模型计算风险比(HR)及其95%CI。结果纳入分析的438 443例研究对象随访11.1年共发生死亡34 661例。与从不饮茶者相比, 当前非每日饮茶者和每日饮茶者全因死亡HR值(95%CI)依次为0.89(0.86～0.91)和0.92(0.88～0.95)。分性别分析显示, 饮茶对全因死亡风险的保护作用主要见于男性(交互P<0.05)。与从不饮茶者相比, 当前每日饮茶者死于缺血性心脏病、缺血性脑卒中、出血性脑卒中、恶性肿瘤、呼吸系统疾病及其他死因的HR值(95%CI)依次为0.83(0.76～0.92)、0.82(0.69～0.97)、0.86(0.78～0.94)、1.03(0.97～1.09)、1.00(0.87～1.16)、0.84(0.78～0.90)。在不吸烟且不过量饮酒者中, 每日饮茶与恶性肿瘤死亡风险间不存在有统计学显著性的关联, 但在吸烟或过量饮酒者中, 每日饮茶者死于恶性肿瘤的风...

Association between tea consumption and all-cause mortality in Chinese adults

Objective To investigate the association between tea consumption and the risk of all-cause and cause-specific mortality among Chinese adults.Methods This study was based on China Kadoorie Biobank(CKB).Tea consumption information was self-reported by participants at baseline.Death was mainly identified by linkage to the death registry system.Cox proportional hazard regression models estimated HR and 95%CI.Results With a median follow-up of 11.1 years,there were 34661 deaths in 438443 participants.Compared with those who never drink tea,all-cause mortality HR(95%CI)were 0.89(0.86-0.91)and 0.92(0.88-0.95)for non-daily tea drinkers and daily tea drinkers,respectively.A statistically significant difference was found in the association of tea consumption and the risk of all-cause mortality between men and women(interaction P<0.05).The protective effect was mainly seen in men.Compared with those who never drink tea,daily tea drinkers had a reduced risk of death from ischemic heart disease,ischemic stroke,hemorrhagic stroke,cancer,respiration diseases and other causes of death,and the corresponding HR(95%CI)were 0.83(0.76-0.92),0.82(0.69-0.97),0.86(0.78-0.94),1.03(0.97-1.09),1.00(0.87-1.16),0.84(0.78-0.90).Among never smokers and non-excessive drinkers,there was no statistically significant association between daily tea drinking and the risk of death from cancer.While smokers and excessive drinkers had an increased risk of death from cancer(interaction P<0.001).Conclusions Tea consumers had reduced risks of all-cause mortality and partial cause-specific mortality,but not for the risk of death from cancer.On the contrary,daily tea drinkers with smoking habits and excessive alcohol drinking had an increased risk of death from cancer.