侵袭性真菌病实验室诊断方法临床应用专家共识

侵袭性真菌病的诊断引起临床多学科关注,早期确切诊断是改善患者预后的关键。其方法主要包括真菌直接镜检、真菌培养和鉴定、真菌血清学检查、分子生物学检测和组织病理学检查。为了促进临床医师深入了解并合理应用这些方法,提高侵袭性真菌病诊断水平,我们邀请多学科专家共同编写了此共识。本共识对侵袭性真菌病诊断方法的应用人群、送检要求、结果解读及临床意义进行了介绍并提出建议,强调对于侵袭性真菌病高危患者,应综合应用多种诊断方法、正确取材送检、提高结果解读能力、了解不同方法的临床意义,以便合理应用,更好地服务于患者。

Expert consensus on clinical application of laboratory diagnostic methods for invasive mycosis

Early and accurate diagnosis of invasive fungal diseases(IFDs)has attracted comprehensive attention,which is crucial to clinical outcome.The diagnostic methods include direct microscopy,culture and identification of fungi,serological examination,molecular biology and histopathology,etc.In order to assist clinicians to apply these methods appropriately and improve the diagnosis of IFDs,multidisciplinary experts were invited to discuss this consensus.Suggestions for intended population,testing requirements,explanation of results and clinical significance were composed regarding invasive fungal diagnostic methods.In high-risk patients of invasive fungal disease,it emphasizes to combine multiple diagnostic methods,take samples accurately,interpret results correctly,understand the clinical significance of different methods,and provide better service to IFD patients.