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人血液和尿液中硒元素的形态分析研究进展
引用本文:徐肖雅,丁亮,林少彬. 人血液和尿液中硒元素的形态分析研究进展[J]. 国外医学:卫生学分册, 2012, 0(2): 91-96
作者姓名:徐肖雅  丁亮  林少彬
作者单位:中国疾病预防控制中心环境与健康相关产品安全所,100021
摘    要:硒是人体必需的微量元素,其不同形态决定它在体内的生物有效利用率、毒性和防癌抗氧化作用,因此人血液和尿液中硒元素的形态分析研究具有重要意义。本文综述了近年来人血液和尿液中硒元素形态分析研究进展,详细介绍了样品的前处理技术、色谱分离技术和ICP-MS的检测技术,并对发展前景进行了展望。

关 键 词:人血液和尿液  硒形态分析  联用技术

Speciation Analysis of Selenium in Human Blood and Urine
Xu Xiaoya,Ding Liang,Lin Shaobin. Speciation Analysis of Selenium in Human Blood and Urine[J]. Foreign Medical Sciences(Section of Hygiene), 2012, 0(2): 91-96
Authors:Xu Xiaoya  Ding Liang  Lin Shaobin
Affiliation:Xu Xiaoya,Ding Liang,Lin Shaobin
Abstract:Selenium is an essential trace element for human.Different speciation of selenium determines its bio-availability,cancer chemoprevention and toxicological properties in human body.It is important to develop studies on analyzing the speciation of selenium in human blood and urine.An overview of recent advances and applicable methods for the speciation of selenium in human blood and urine was conducted in this paper,including preparation of samples,liquid chromatography separation and hyphenated with ICP-MS detection.The perspectives of applying HPLC-ICP-MS technique for the speciation analysis of elements are discussed.
Keywords:human blood and urine  speciation analysis of selenium  hyphenated technique
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