Varicella zoster meningitis in a pregnant woman with acquired immunodeficiency syndrome |
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Authors: | Jayakrishnan Asha Vrees Roxanne Anderson Brenna |
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Affiliation: | Department of Obstetrics and Gynecology, Brown Medical School/Women & Infants' Hospital of Rhode Island, Providence, Rhode Island 02905, USA. ajayakrishnan@WIHRI.org |
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Abstract: | Between 6000 and 7000 women in the United States infected with human immunodeficiency virus (HIV) give birth annually. It is well known that HIV-related immunosuppression significantly increases the risk for acquiring opportunistic infections (OIs). However, there is limited information regarding the relationship of pregnancy in the setting of HIV/AIDS infection, subsequent development of OIs, and maternal and fetal outcomes. A pregnant 36-year-old woman with AIDS was diagnosed with varicella zoster meningitis. Weight-based therapy with acyclovir was initiated with clinical improvement in symptoms. Care of a pregnant HIV-infected patient with an OI poses a unique diagnostic and therapeutic challenge for clinicians. Early diagnosis and initiation of appropriate treatment may provide an opportunity to improve both maternal and fetal outcomes. |
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