Burn size determines the inflammatory and hypermetabolic response |
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| Authors: | Marc G Jeschke Ronald P Mlcak Celeste C Finnerty William B Norbury Gerd G Gauglitz Gabriela A Kulp David N Herndon |
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| Affiliation: | (1) Shriners Hospitals for Children, 77550, 815 Market Street, Galveston, TX, USA;(2) Department of Surgery, University Texas Medical Branch, 77550 Galveston, TX, USA |
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| Abstract: | Background Increased burn size leads to increased mortality of burned patients. Whether mortality is due to inflammation, hypermetabolism or other pathophysiologic contributing factors is not entirely determined. The purpose of the present study was to determine in a large prospective clinical trial whether different burn sizes are associated with differences in inflammation, body composition, protein synthesis, or organ function. |
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