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正确认识OCT血管成像技术的临床应用价值
引用本文:王敏,周瑶.正确认识OCT血管成像技术的临床应用价值[J].中华实验眼科杂志,2016(12):1057-1060.
作者姓名:王敏  周瑶
作者单位:复旦大学附属眼耳鼻喉科医院眼科, 上海,200031
摘    要:OCT血管成像(OCTA)是一项无创、快捷的血流检测技术,目前主要用于视网膜脉络膜的血流成像.与传统的荧光素眼底血管造影(FFA)和吲哚青绿血管造影(ICGA)技术不同,OCTA无需静脉注射造影剂就能够对血流信号进行探测和量化分析,并且能够分层观察和判断视网膜脉络膜的血流改变情况,因此OCTA比传统的眼底血管造影技术提供的血流信息更多、更准确.OCTA作为一项具有革命性突破的新技术,在眼科血管性疾病的诊断及血流改变有关眼病的发病机制探讨方面具有划时代的意义.但是,任何新技术的临床应用都有其限制性和局限性,如OCTA观察的眼底范围并不如FFA和ICGA大,且检查和读图过程中也受到一些因素的影响.充分了解OCTA的成像原理和成像特点有助于眼科医师更好地了解视网膜脉络膜疾病、青光眼和神经眼科疾病的血流改变,并加深对这些疾病发病机制的认识,同时利用该技术对相关眼病进行有效监测和随访.

关 键 词:血管摄影/方法  生物技术评估  光学相干断层扫描  视网膜血管/生理病理  脉络膜新生血管/诊断  视神经  荧光素眼底血管造影  吲哚青绿血管造影

Correctly understanding the clinical value of optical coherence tomography angiography
Abstract:OCT angiography (OCTA) is a non-invasive imaging technique for detecting blood flow information of the retina and choroid.Dye injection is not needed with OCTA,which is different from fundus fluorescein angiography (FFA) and indocyanine green angiography (ICGA).OCTA is able to observe blood flow in different retinal and choroidal segmentation slab.This revolutionary breakthrough in OCTA algorithm provides more and more accurate blood flow informations in the diagnosis of ocular vessel diseases and the study on pathogenesis of some vessel-related eye diseases.However,like other biometric technology,OCTA has its limitations and shortcomings,for example,OCTA presents a smaller observational area than FFA and ICGA,and some factors affect the imaging quality and cause misdiagnosis during the examination and reading image.Fully understanding the principle of OCTA and its image features are helpful for eye doctors to better interpret the blood flow changes of retinal diseases,choroidal diseases,glaucoma and neuro-ophthalmic diseases.Ophthalmologists should correctly apply this imaging tool for a better monitoring and following up of these diseases.
Keywords:Angiography/methods  Technology assessment  biomedical  Tomography  optical coherence  Retinal vessels/physiopathology  Choroid neovascularization/diagnosis  Optic nerve  Fundus fluorescein angiography  Indocyanine green angiography
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