| 玻璃体替代物的研究进展 |
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| 引用本文： | 江枫. 玻璃体替代物的研究进展[J]. 中华实验眼科杂志, 2016, 0(4): 380-384. DOI: 10.3760/cma.j.issn.2095-0160.2016.04.020 |
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| 作者姓名： | 江枫 |
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| 作者单位： | 300052,天津医科大学总医院眼科 |
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| 基金项目： | 天津医科大学总医院青年孵育基金(ZYYFY201409)，TMUGH Funding(ZYYFY201409) |
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| 摘 要： | 复杂的玻璃体视网膜手术中,常常需要玻璃体替代物支撑玻璃体腔、维持眼内压.气体、膨胀气体、全氟化碳液体、硅油是现代玻璃体视网膜手术中常用的玻璃体替代物,胶原、透明质酸、水凝胶等被尝试用作长期的玻璃体替代物.理想的人工玻璃体一直是研究的热点.本文就目前应用的以及仍处于实验阶段的玻璃体替代物进行综述,根据其功能、构成及特性进行分类,并讨论它们的临床应用及优缺点,同时定义理想人工玻璃体的标准.
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| 关 键 词： | 玻璃体替代物 水凝胶 玻璃体/手术 |
Recent advance in vitreous substitutes |
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| Abstract: | In complicated vitreoretinal surgery,vitreous substitutes play a major role in maintaining intraocular pressure.Air,expansion gases,perfluorocarbons liquid,and silicone oil are frequently used in modern vitreoretinal surgery.Long-term vitreous substitute has been attempted with collagen,hyaluronic acid,natural hydrogel polymers and so on.However,an ideal vitreous substitute is being requested for a long time.This review focused on the currently available vitreous substitutes,as well as those in the experimental phase.These compounds were classified based on their functionality,composition,and properties.The clinical use,advantages,and shortcomings of the various substitutes were discussed.Finally,the criteria for an ideal vitreous substitute was defined. |
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| Keywords: | Vitreous substitutes Hydrogel Vitreous body/surgery |
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