| 早产儿视网膜病变血清代谢通路研究进展 |
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| 引用本文： | 李慧林,张国明,张福燕,曾键. 早产儿视网膜病变血清代谢通路研究进展[J]. 眼科新进展, 2016, 0(9): 881-884. DOI: 10.13389/j.cnki.rao.2016.0237 |
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| 作者姓名： | 李慧林 张国明 张福燕 曾键 |
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| 作者单位： | 550000 贵州省贵阳市，贵州医科大学附属医院眼科（李慧林，张福燕）；518040 广东省深圳市，深圳市眼科医院（李慧林，张国明，曾键） |
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| 基金项目： | 深圳市科创委基础研究项目(编号:JCY20140414114-853651、CXZZ201305161-6181591)Key Project of Shenzhen Science and Technology Innovation Committee (JCY201404-14114853651 |
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| 摘 要： | 早产儿视网膜病变（ｒｅｔｉｎｏｐａｔｈｙｏｆｐｒｅｍａｔｕｒｉｔｙ，ＲＯＰ）是一类发生于早产、低体质量儿的视网膜血管异常增殖性致盲眼病。目前，ＲＯＰ发病机理尚不清楚。深入研究ＲＯＰ病理生理变化和发病机制，并采取有效措施阻断这一过程，将有利于从根本上预防ＲＯＰ或阻止ＲＯＰ严重病变的发生。寻找可用于ＲＯＰ诊断的潜在血清特异性标志物，可为ＲＯＰ发病机制研究和临床试验奠定基础。本文对ＲＯＰ血清代谢通路研究新进展进行综述。
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| 关 键 词： | 早产儿视网膜病变 血清 代谢产物 |
Research progress on serum metabonome in retinopathy of prematurity |
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| LI Hui-Lin,ZHANG Guo-Ming,ZHANG Fu-Yan,ZENG Jian. Research progress on serum metabonome in retinopathy of prematurity[J]. Recent Advances in Ophthalmology, 2016, 0(9): 881-884. DOI: 10.13389/j.cnki.rao.2016.0237 |
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| Authors: | LI Hui-Lin ZHANG Guo-Ming ZHANG Fu-Yan ZENG Jian |
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| Affiliation: | Department of Ophthalmology , Affiliated Hospital of Guiyang Medical College ( LI Hui-Lin , ZHANG Fu-Yan ) , Guiyang 550000 , Guizhou Province , China ; Shenzhen Eye Hospital ( LI Hui-Lin, ZHANG Guo-Ming, ZENG Jian ) , Shenzhen 518040 , Guangdong Province . China |
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| Abstract: | Retinopathy of prematurity ( ROP) is a vascular proliferative retinopathy with unmatured and low weight infants. At present, the pathogenesis of ROP is not clear. Therefore , thorough studying the pathophysiological changes and pathogenesis of ROP, and taking effective measures to block the process , will be helpful to prevent ROP or prevent the occurrence of severe ROP. Exploring the potential serum specific markers for diagnosing ROP can lay the foundation for the research of pathogenesis and clinical trials of ROP. This article reviews the research progress on serum metabonome of ROP. |
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| Keywords: | retinopathy of prematurity serum metabolites |
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