Mismatch Negativity in Children with Autism and Typical Development |
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| Authors: | Michelle A Dunn Hilary Gomes Judith Gravel |
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| Institution: | (1) Department of Neurology, Albert Einstein College of Medicine, 1410 Pelham Parkway South, Bronx, NY 10461, USA;(2) Department of Otolaryngology, Albert Einstein College of Medicine, Bronx, NY, USA;(3) Department of Pediatrics, Albert Einstein College of Medicine, Bronx, NY, USA;(4) Present address: Department of Psychology, City College, City University of New York, New York, NY, USA |
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| Abstract: | Children with autism are often characterized as having abnormalities in auditory processing. This study examined automatic
and active processing of simple auditory stimuli in children using a component of event related potentials, the mismatch negativity
(MMN). Amplitude of MMN in children with autism was significantly smaller than in children with typical development in unattended
conditions. However, children with autism exhibited a typical amplitude MMN when attending to the stimuli. Receptive language
and MMN were not related in children with autism. Findings support the idea of abnormal automatic auditory processing by children
with autism. Auditory discrimination of infrequent changes in streams of sounds appears to be accomplished through a different
mechanism than in typical children, specifically through the investment of attention. |
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| Keywords: | Autism Neurophysiology Event-related potentials Mismatch negativity Automatic processing |
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