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Defective peroxisomal proliferators activated receptor gamma activity due to dominant‐negative mutation synergizes with hypertension to accelerate cardiac fibrosis in mice |
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| Authors: | Min Zhang Anjana Siva Sergio Rodriguez‐Cuenca Stefania Carobbio Agnes Lukasik Margaret Blount Steve O'Rahilly Sarah L. Gray Ajay M. Shah Antonio Vidal‐Puig |
| Affiliation: | 1. Cardiovascular Division, King's College London British Heart Foundation Centre of Research Excellence, 125 Coldharbour Lane, London, SE5 9NU UK;2. Metabolic Research Laboratories, Level 4, Institute of Metabolic Sciences, Box 289, Addenbrooke's Hospital, Cambridge, CB2 0QQ UK;3. Northern Medical Program, University of Northern British Columbia, 3333 University Way, Prince George BC, Prince George, BC, V2N 479 Canada |
| Abstract: | |
| Keywords: | Hypertension Left ventricular hypertrophy Interstitial fibrosis Dominant‐negative PPARγ Lipodystrophy |