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Lipase inhibitory activity in alcohol extracts of worldwide occurring plants and propolis
Authors:Niels Peter Möller  Nils Roos  Jürgen Schrezenmeir
Affiliation:1. Max Rubner‐Institut, Federal Research Institute of Nutrition and Food (location Kiel), Department of Physiology and Biochemistry of Nutrition, Hermann‐Weigmann‐Str. 1, 24103 Kiel, Germany;2. Current address: Skretting Aquaculture Research Centre, Stavanger, Norway. Presented in part at the ‘Milchkonferenz 2005’, held in Kiel, Germany, on 29–30 September 2005.
Abstract:In the search for lipase inhibitory agents, 144 alcohol plant extracts and propolis were screened for pancreatic lipase activity in vitro using methods with methylresorufin and triolein as substrates. Ethanol extracts of Linum usitatissimum (oil flax) and Helianthus annuus (sunflower seeds) showed the strongest lipase inhibitory actions with ID50 values of 1:370 and 1:166, respectively. Copyright © 2008 John Wiley & Sons, Ltd.
Keywords:pancreatic lipase inhibitor  metabolic syndrome  plant extracts  functional food  propolis
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