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Changes in stiffness and biochemical composition of the pericellular matrix as a function of spatial chondrocyte organisation in osteoarthritic cartilage |
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| Authors: | M. Danalache R. Kleinert J. Schneider A.L. Erler M. Schwitalle R. Riester F. Traub U.K. Hofmann |
| Affiliation: | 2. Laboratory of Cell Biology, Department of Orthopaedic Surgery, University Hospital of Tübingen, Waldhörnlestraße 22, D-72072 Tübingen, Germany;3. Medical Faculty of the University of Tübingen, D-72076 Tübingen, Germany;4. Winghofer Medicum, Röntgenstraße 38, D-72108 Rottenburg am Neckar, Germany;6. Department of Orthopaedic Surgery, University Hospital of Tübingen, Hoppe-Seyler-Strasse 3, D-72076 Tübingen, Germany |
| Abstract: | |
| Keywords: | Osteoarthritis Cellular organisation Articular cartilage Pericellular matrix Atomic force microscopy Stiffness AFM atomic force microscope BC big clusters DS double strings DMEM Dulbecco's modified Eagle's medium ECM extracellular matrix ELISA enzyme-linked immunosorbent assay FDR false discovery rate OA osteoarthritis PBS phosphate-buffered saline PCM pericellular matrix SC small clusters SS single strings |
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