中耳胆脂瘤扩散加权成像诊断研究进展

扩散加权成像（DWI）通过水分子的扩散在MRI图像中产生对比度，中耳胆脂瘤是一种角化性鳞状上皮异常生长的疾病，其在DWI上显示为特异性的高信号。已有多项研究支持将DWI作为中耳胆脂瘤的辅助检查手段应用于临床，认为其无论对于初发性中耳胆脂瘤还是复发性中耳胆脂瘤都具有很高的准确性，甚至可以一定程度上取代中耳胆脂瘤术后的二次探查手术。笔者就近年来中耳胆脂瘤诊断的扩散序列进展，以及扩散技术的定量分析与序列融合进行综述。

Research progress on application of diffusion weighted imaging in diagnosis of middle ear cholesteatoma

Diffusion-weighted imaging (DWI) produces contrast in MRI images through the diffusion of water molecules. Middle ear cholesteatoma is a keratotic squamous epithelial dysplasia, which shows specific hypersignal on DWI. A number of studies have supported the clinical application of DWI as an auxiliary examination method for middle ear cholesteatoma. It is considered that it has high accuracy for both primary and recurrent middle ear cholesteatoma. It can even replace the secondary exploratory operation after middle ear cholesteatoma to a certain extent. This paper reviews the progress of diffusion sequence in the diagnosis of middle ear cholesteatoma, as well as the quantitative analysis and sequence fusion of diffusion technique in recent years.