青年非瓣膜性房颤患者危险因素分析研究进展

心房颤动（atrial fibrillation,AF）作为最常见的心律失常之一,虽然AF以老年人多见,但越来越多证据显示在青年人群中非瓣膜性房颤（NVAF）的发病率不断提高。更好地认识青年人NVAF危险因素,有助于改善患者临床预后和生活质量。本文综合国内、外相关研究,总结青年NVAF发生、发展的不可控因素（种族、性别、年龄等）和可控因素（吸烟、嗜酒、肥胖、能量饮料摄入、高负荷运动、阻塞性睡眠呼吸暂停综合征、肥厚性心肌病、先天性心脏病、外伤性颅内出血等）,并着重对各个可控危险因素的流行病学和发病机制上进行探讨,以更好地指导青年NVAF Ⅰ级和Ⅱ级预防。

Research progress in analysis of risk factors in young patients with non-valvular atrial fibrillation

Atrial fibrillation (AF) is one of the most common arrhythmias. A better understanding of the risk factors of non-valvular AF is helpful to improve clinical prognosis, as well as life quality of patients. Non-valvular AF occurs in the young and older populations. Modifiable non-valvular AF risk factors, including race, gender and age, and unmodifiable AF risk factors, including smoking, alcohol abuse, intake of energy drinks, obesity, intense exercise, obstructive sleep apnea syndrome (OSAS), hypertrophic cardiomyopathy (HCM), congenital heart disease (CHD) and traumatic intracranial hemorrhage (TICH) for young people are summarized in this review. For a better primary and secondary prevention for non-valvular AF focused in the young, this article focuses on analysis of epidemiology and pathogenesis of all controllable factors.